Service Providers for MSH2
MSH2 (MutS Homolog 2) is a gene involved in DNA mismatch repair, helping to correct errors that occur during DNA replication. Mutations in the MSH2 gene are associated with Lynch syndrome (hereditary nonpolyposis colorectal cancer or HNPCC), which significantly increases the risk of colorectal, endometrial, ovarian, and other cancers. Testing for MSH2 mutations is part of genetic screening for Lynch syndrome, which aids in identifying individuals at high risk for cancer. The test typically involves a blood or tissue sample for genetic analysis. Identifying MSH2 mutations helps guide cancer prevention, screening, and treatment strategies for affected individuals and their families.